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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42776edcdfeef8a612ea431b6914e1d824e755a6fcb00cb7e767b5405a89d9f9' 
  AND token = '7RpW8GdKg45lEb8O18u0v93z8PmritwemUWuNA9+EWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}