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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed34219a9deee146dcf6f050c91d28954c63fc2bec8b125a7be3211792037289' 
  AND token = 'N6Hmpc0Y9Nnwh2rmowfzLWOX5/2wMgBvc6ZL6RecQ1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}