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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6f5012d302c730b21f916bff2226287b7a2fa08f262771b5c8995e59c684bd' 
  AND token = 'Jb8XKTZtehwP06AP/VAiTNOVA+RXuYAUbncJoTysfWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}