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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dfa7db881a883ada1958558f0a87542aea33be21339cdf3b12e9e76aae0d5eb' 
  AND token = '/fB/4v3V6YdXXyd/Xl5DUkLnAkjPHIPhcZAVewV+Rjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}