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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0774b5a94de0032518f70e79098f015f366d94c886bbc0b99ee4b226b1995ee7' 
  AND token = '2CmDksf6pP1XlDoumYrp2KMiNdxexEWUpbCwntGe/4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}