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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a8f1d84d6ff3bfd37307f61e04f4e5b32f128b28217ba9f5b1b20ac8318b2fb' 
  AND token = 'j9y4Ctvv4lfGe77FQmL0URNlyA8kn5nxNbOrZFMSnyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}