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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a38b1c22ea85a90964994e904f7d25291b80cc6c09ef85f4e2c9f0627d3a2b4' 
  AND token = 'rkMVpXTHlavHAILlC8BsKe682tZk1tzzdNvckEunRj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}