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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74940005f3c20985f9a44f5f22c811630a6dc8e812572d5c704d48047c77451' 
  AND token = 'zzyWpLdMwF3WeB/w7SIyOJgEez5LfxqTbwCy4Xp1Vjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}