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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f250aab89b5673f88aeda23eff0e0f72146246bfb890846089c61bd44dd66212' 
  AND token = 'rl9dNe+BMLOhsYg8VX8Q4pvI03wRWvX/s+QEKbruoQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}