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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff9889b29320cf06be86b20e8e024b714cb5af17fdda8579b0a0e224d3fa2bf' 
  AND token = '0a9VwMUjlIs0BHTaOWzV7vqC3EpROAKmBi8l03GQXLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}