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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7665ebca8d2afd7f591d092c82a562e5f8bb593bfba0365776b98dde0b76f7d' 
  AND token = 'YTg9LX9fDFhKI3XtCLOh0oJRkil8gPXdBB+U4r5TZMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}