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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb46ba1d55db69896a01d2c37a1554b090150b1c0f1a6de695d715bf31a5355' 
  AND token = 'mHAKcc6/VNA0L9d5DKAAES4h2Nuc3LWh37IEWZpKRMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}