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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65567de5108a68a137c15c4eb2bed302be8ecc14ac91440aa0c88572bc102bd3' 
  AND token = 'zuaIiU7Ci8CIcSsdDrw0zoVlt48605mP8WQp/lwY6UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}