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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9e93986ba1cca9e48875f6f90105994ea63bac647326ea633b8f5a87fc26c1' 
  AND token = 'OA3DTPvnP/WVvbcPej766FjWEnRiycCLTl2LaYL3fXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}