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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36eae29cd2438e344a3eea760bb071afcc177461b51a886f131e7fae10f309f6' 
  AND token = '70zg3ZGhOgl48DMaKTuMsN443FP5rryEQ8zHPJsjHQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}