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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1252e13bb752d1e43df3ff6d5bad731b9232ab7497940d54069cecb593f28f17' 
  AND token = 'kepswPZ1Wo90vCOVW/kay4B2Hw3rED1GC6CLGUVmJFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}