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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b0a0a6b6018f093979d0a53e026ef7ba0e9769022f93f3c81503dadaf6c183' 
  AND token = 's15AQv7kvmevn/BibBF7XEwrUJFnd4bTu9w714pLFAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}