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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e01f933b91f23d54b6e95e402cbfc69e1189a1ed6dce9e4ea4e07b71c280cdf' 
  AND token = '2L0s8A8dHK9Lwf4uAglkDa+z1gqyCO2FDAr9TKLoDUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}