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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ade2f43b745b2b2c52cb85602bd2bcf0a1dbbeeb0e4fe6a6471518249f5d85' 
  AND token = 'HTladN2BrB68jC+p35eBovSK9sS2gXTPOBeSkoMlvl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}