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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46dde43bfef536bf7883b5d8df5d01ad9953734cdbde84580550fbefacf1b1e' 
  AND token = 'NmsMR2Xq/+LQBQjEzL3qD2/nn84av5/8WGZIVfyZ15o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}