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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6eaa17b803bd562a34216716c5fd82eb74f404542de85562ea449cf28390c54' 
  AND token = 'GpE2Yk3UIhLbBEu0GwxA3m5rYAODGmxbU/IbBmrkrfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}