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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a346cbfa05672a20142d42614c78c5d417ca00462278d0c07c35b73bcb8e1bf' 
  AND token = '7c0rcXocOf6Gak7g0dd2ZJT8SR3iAcbXGP8Tnd2UxT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}