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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a740340685a1ac04e6feb0aeae2989457c55e0fe3e1b1b9396e677c998e8e1a' 
  AND token = 'LU7di2YBhKwcG5y/A4anII1xSn3xR+Ha9xuItoHxbzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}