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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d255638fd0c1910e5a55a972fc899b6f474f5895b50c96313521f12e4063d9f' 
  AND token = '6wE4uwo9+6bCvjvv3NlWat3zH6fykyG7NGQsTir5rs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}