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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e47f46d195a836743a8335291277c9f996ec80cbb816c3f1e139ab9f7e43af' 
  AND token = 'XcDoddVaG5LotQoAPGiGGg/0oiF1lrTs/Nfo9mEdi5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}