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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6c8730407b54036ac64910fe53ba5ab15c0966ec1e4c416775485e894768c3' 
  AND token = 'JUexHaLM1lBUvFDqMiLlm/kdo/ip5OPpRQzWOWon5Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}