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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434e4455260f688b43ecb440988ed2b5dd7d104c1c0a845c17a558c50a6fc48c' 
  AND token = 'QcMc8TLFVEWKVQXByrOE9n84fMR1T9VGJYLcJLClIn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}