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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1e57be8514dea6663cca540635e5b47e6160a8c03799eeaca5c571470b4219' 
  AND token = 'JbcxS/9IwCa2Zn6wND2mdbkPim7M/ZIqEJ3fH4IL6Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}