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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12834e81a741f2971f1c01f180b66eb15a7d029ee94b15c762ad6381ec01987' 
  AND token = 'l0icG6uOZUzaSB2FdxEKPdV2pPvRVICuw76svrsSjcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}