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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e4bee0829c8e469b01142c75edd3b0aad25e270e6096507ebd1bc6d72cf39e' 
  AND token = 'EBqq/NBKsuRFPWH6tmm5CCF8SzcBWD3JiVCCB/ViYWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}