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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af6df8a33c308b8fb685f80221d2f240eb73a02d2dfb6d54e4958464a936893' 
  AND token = 'JqmG4LYerfnvYJY0MSba1Iuva4r29DcZyrixmCUIdu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}