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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d37ca7f42ff47b3b88ae1d0b8497d9c62ecdffdeb025766b41047703e9c905' 
  AND token = 'eZO8l1wNz/nTdmJz7iNelgso2LUOMeErc4H1zmkrw5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}