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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aced99abd1221fcf1a0448bc074012c15ce126624b93a8e66f7295955555a284' 
  AND token = 'Qc2Glvwt06dpYjlpgdO4rh6jMuyB0h4CcH8A2a6E4/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}