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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37c256755ca6227cba2e061b4aa53c5ec7db36706c84f0b6279a2d9b4227960' 
  AND token = 'EpcrUYk14EDGsZB8qaYyy278XK295cEUnZzSO6UOxHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}