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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42c0ff8ddb69a4f0115cf0548cb95d0a00bc8ee0fd33abb98f27aefa5e35742' 
  AND token = 'XS2i0BKTxSciqVQGCbuiFTE+0c5EhsP3rGPEzwccqIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}