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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03574bbc19bf0e2d7735a9fb14f5470beba7afed8c829f4fb0f2e9f83b4073d7' 
  AND token = 'I6wdyXdUXpMCysGCW/cM2ot/6YU0iK99uFo2RNU0T6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}