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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b2eb0b6097df7ae7ebec6cc9c1e3fcb81c016a161d31cfa17e53a3e1dd6bb7' 
  AND token = 'miXwuL189ZBtPU3GWk6jxOK+E5RajxQMucP77lLdpN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}