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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75200786351fc6c1422eb61a08ae114384d86bb5d41d8b1e902ecdb63b4a5b9b' 
  AND token = 'doVmpY3F4+dM3DgzR44WJAkOL23yoNeNLm5poqS2178=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}