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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64723567cddf9483b32eaf4e157a5b2737bcbcabcbc5c53587686af069810e36' 
  AND token = 'geRTC3Ub2iKIqRTo5yXcCOm4358qT/rMQuTecfIfM14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}