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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b8bd0fe27bb1d11c7c27c91ad9c37c133216241f386000629aeb54f6ccf39e' 
  AND token = 'V2oW7xRPXgzrum+r+VqUTX6QgVb+ApDSkmz5w6eOydk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}