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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280aaa410f762704fae63bb6b098298dee0bee8a9ad83c892cbfa2705eeabc01' 
  AND token = 'mBkuHJfkSz4SsZF9y7hgtRrSg89djpIsegqsaIlu180=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}