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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f2ea9886ec6792541cb07a1eac14b6fb8c9320010fa3d66eccd6b799030b0f' 
  AND token = '4XCs84UJXaBM2A2AC09nL9Q0jwuTZp7idDo5W6IP0nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}