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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144f544109fffcee90a794ae6151d21fff229de0c9d56d9fe652d7890c67d4fe' 
  AND token = 'IjVumKVLl8t4muelwW1BQ+c1K8yW4DXfbgxvb18RbP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}