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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12c78d8bb494e42c0eec8c2cdede6b5c1b98c4392cbf774485282d5cfa2eb0d' 
  AND token = 'SIzSXTdKMRKr4dDMcA+ihX+lG+4tobKLRhCTQqna31c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}