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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab001f9cddb4483b8ad0098f4af9496f8645856beb9d0484a8e8d1796da4430' 
  AND token = 'jB9SPg8+AwKpWT/efe3/yeA8FrP9O1/nIb7HbPGqOTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}