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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a921fc8d9e4768bd4dd527b8fce971b2602bb4b9b3c79c3df00b3c319c43b968' 
  AND token = '2MPCiAKfjvZSxkojY4Suz+hAVDuC9AsY8w1bncPg2uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}