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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3b523a5c8115a569dd11235d99db008a9bf80ee15a44d518ab67f24b65b044' 
  AND token = 'Ujq9n2pvldOHKVQgEEAxEc1sgc9d9Bp31z4azqHwW/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}