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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1215a7bcc289e9b207e2ed3ff16119cd454e6c2f15ae42d24b2c1e0320a901' 
  AND token = 'ZLzewuUiVA0TcaRiPUi8+rL5o4+sf4GIWy2oxCPJgiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}