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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457f3e71a3207727f632f06ea994759281a90f2ce154b7f12e10e877fd60ccb8' 
  AND token = 'LU1CLj15V+zLXMIohGCWMwrWluH1uomxDuJ7Zx6E9iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}