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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628636a3246eac9ac4f6f2a5ec66041655640137d5a0b2da4093b3dbc5931583' 
  AND token = 'pOk/evRDr+WQdZXx9s0pAVaKG8wFa8reYlnauD/0JbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}